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Posts Tagged ‘immune system’

Tracking H1N1 Vaccine Side Effects

Monday, October 26th, 2009

dr_manny_blog2There has been a lot of push back when it comes to the H1N1 flu vaccine. Of course, as with any medication, there could be side effects because not all immune systems are created equal.

But what people have to remember is their reasons for not supporting the vaccine – mainly because of the fear that it was rushed and long-term side effects are not yet known – are some of the same reasons preliminary reports of possible side effects could also be coincidental. For example, if someone has a heart attack after receiving their H1N1 flu shot, are they going to assume it’s directly related to the vaccine or attribute it to unhealthy lifestyle decisions?

The Associated Press recently published an article on this topic that looked at how the government will be intensely tracking the side effects of this vaccine and separating legitimate medical concerns from inevitable coincidences.

This is a proactive plan. The government is going to be putting information together for the public in an effort to stop the spread of false rumors and try to put the public at ease.

One major focus will be miscarriage since they are encouraging pregnant women to get the vaccine and miscarriages are quite common anyway.

Like the seasonal influenza vaccine, medical professionals expect the side effects associated with the H1N1 flu vaccine should be minimal. The most common side effect with all flu vaccines is soreness at the injection site, and sometimes people feel achy.

Many Americans are concerned about the safety and efficacy of the newly developed H1N1 flu shot because of a similar vaccine that was linked to a swine flu-like outbreak at Fort Dix in 1976.

Guillain-Barre occurs naturally following upper respiratory illnesses, digestive illnesses and on rare occasions – is associated with drugs and vaccines. However, the frequency is still 1-2 per 100,000 people.

I’ll be keeping a close eye on this, and if anything is reported, I’ll be the first one to let you know.

Herbal Germ Fighters

Wednesday, October 21st, 2009

Medicine Hunter Chris Kilham (116 x 149 - on color)The world is alive with germs of all kinds, especially bacteria and viruses. Most of the time our bodies do an excellent job of fending off these microbes. This self-defense is due to the immune system, which notices any pathogen (disease-causing agent), and attacks it with immune foot soldiers including macrophages, lymphocytes and phagocytes. But sometimes our bodies can’t fight off disease-causing agents without help.

This is when certain herbs can come in handy.

 

 

Working Two Ways

Mixed spicesHerbs can help to fight germs in two ways. On the one hand, herbs can bolster the immune system so that our bodies can respond more powerfully to germs when they attempt an invasion. On the other hand, some herbs can even kill germs outright. Let’s examine a few common germ-fighters in the herbal world.

Ginger

This common root contains two classes of compounds known as gingerols and shaogals.  These are powerful antioxidants, so they help to prevent premature destruction of cells, a very handy function indeed. But these same agents also increase the proliferation of immune cells, thus providing more ammunition for the body to ward off disease. Ginger also contains a group of compounds called sesquiterpenes, which kills rhinoviruses, the agents that cause colds. So when you have a cold, several bracing cups of fresh ginger root tea can help you to reduce the severity and duration of that unwanted event. Ginger tea also relieves a sore throat, providing immediate relief.

Green Tea

Many people know green tea simply as a pleasant, low-caffeine beverage. But green tea’s antioxidant compounds, called the polyphenolcatechins, also boost overall immune function.

One of the functions of these compounds is to inhibit tumor growth. Studies of human populations show decreased incidence of some types of cancer among green tea drinkers, and animal studies show specific immune activity against various types of tumor cells. This is not to say that green tea is a cancer cure. But drinking green tea daily can reduce your risk of cancer overall, by enhancing immune function. This same immune-enhancement helps to protect you from various pathogens in the air and in water and food.

Elderberry

More spicesIn some small studies, elderberry has demonstrated anti-flu activity. This is due to a group of antioxidant flavonoids in elderberry thatbind to the influenza virus and prevent infection. Some researchers question the real efficacy of elderberry as a flu-fighter, but it does demonstrate some value. A recent study of elderberry extract and the (new scary) H1N1 virus showed that the antioxidant compounds in the berries inhibit the proliferation of that virus. While further work must be done on this, the study suggests that at least, elderberry may help to reduce the activity of this flu.

 

Garlic

Sometimes called the stinking rose, garlic has long occupied a special place in natural healing. This fragrant and pungent member of the allium family enhances overall cardiovascular health, fights various types of cancer cells well, and is a potent immune booster. But garlic goes beyond this, actually killing many of the types of bacteria that cause food poisoning. Heavy use of garlic is prevalent in places and cultures where food preparation hygiene may be poor, and where refrigeration is not always available. Adding fresh-pressed garlic into food, or cooking with garlic, may prevent sickness due to bacterial contamination. And if you have a cold, press a clove of garlic into a cup of hot water, add the juice of a lemon, mix in a teaspoon of honey, and drink it down. This shot to the immune system will help you to get rid of the cold faster.

Hot Peppers

Not everybody likes hot peppers, also known as chile peppers. But for chile lovers, these peppers not only pack a hot wallop, they provide immune support as well. You can use hot peppers fresh and raw, cooked, or as hot sauces. Like garlic, hot peppers enhance immune function, thereby making your body more resistant to disease. They do so thanks to the presence of capsaicin (think really hot), the oil that gives peppers their heat. This is also the same oil used in topical capsaicin arthritis creams. Like garlic, hot peppers also kill bacteria outright. In West Africa, people commonly make a paste consisting of finely ground hot peppers, ground coarse salt, and minced onions, which have a similar effect as garlic.  This paste is eaten in small amounts alongside food that might contain bacteria.

Herbal Pick of The Week

I derive absolutely no income or favors from the makers of Tabasco sauce, but I will say that this common and well-loved hot sauce is a regular part of my personal health regimen. Made only with tabasco variety hot peppers, this sauce shows up almost everywhere in the world. Not only does Tabasco contribute zip to foods, but it’s a great natural medicine to carry when you travel. You can definitely find hotter and more exotic sauces, but in my book Tabasco reigns supreme.

Hippocrates famously stated  “Let food be thy medicine.” In the herbs above, we have common foods that also play valuable germ-fighting roles in nature’s medicine chest.

Chris Kilham is a medicine hunter who researches natural remedies all over the world, from the Amazon to Siberia. He teaches ethnobotany at the University of Massachusetts Amherst, where he is Explorer In Residence. Chris advises herbal, cosmetic and pharmaceutical companies and is a regular guest on radio and TV programs worldwide. His field research is largely sponsored by Naturex of Avignon, France. Read more at www.MedicineHunter.com

How Healthy is Your Child?

Monday, June 22nd, 2009

tanya_zuckerbrot2As most of you know, children are notoriously fussy eaters.  However, there are ways to insure that your child is consuming a healthy diet despite what they might think.  Many of the foods that your child already loves are healthful and nutrient-dense.  All it takes is a little knowledge to make some informed choices and your child will be flourishing.  Here are some examples of typical kids’ foods that actually pack quite the nutritional punch:

1. American cheese: Kids love the color and the feel of this food, but there’s a lot for you to love about it too.  American cheese provides both calcium and protein, which is vital to their bone and muscle growth, as well as skin and tissue repair. 

2. Chocolate milk: Milk is another excellent example of a good source of calcium and protein, as well as many other vital nutrients. Children need at least 2 cups of milk each day to meet their needs.  While that may be hard to do with plain, white milk, studies show that by flavoring their milk, not only is consumption increased, but the tendency for kids to drink sugar-laden soft drinks and juices is reduced.

3. Breakfast cereals:  While there are many breakfast cereals on the market that have little-to-no nutritional value and tons of sugar, there are brands that are quite healthy. Kids love cereal because it’s bite-sized and crunchy, and if you choose the brands with the most amount of fiber and whole grains, they’ll be getting a lot more nutrition than they’ll ever realize.  A high-fiber cereal means that a lot of nutrients are still intact and have not been stripped away during processing.  Most cereals are also fortified with B-vitamins, important for a healthy immune system.

4. Yogurt:  Another calcium and protein source, yogurt also contains natural, beneficial bacteria that are important for normal gut functioning and integrity.  This helps to keep away the tummy aches.  You can find yogurts in a wide array of kid-friendly colors and flavors.

5. Hamburgers:  Most of us equate hamburgers with fat and an unhealthy diet. However, hamburgers happen to have a lot of nutrition in them.  Especially when purchased and prepared at home, look for the leanest ground beef and make them yourself.  Beef contains nutrients such as iron and zinc, and is an excellent source of high-quality protein.

Tanya Zuckerbrot, MS, RD is a nutritionist and founder of www.Skinnyandthecity.com.    She is also the creator of The F-Factor Diet™, an innovative nutritional program she has used for more than ten years to provide hundreds of her clients with all the tools they need to achieve easy weight loss and maintenance, improved health and well-being.  For more information log onto www.FFactorDiet.com.

A New Approach to Cancer

Wednesday, June 3rd, 2009

siegel1The problem with trying to treat cancer has always been that the body does not accept cancer as something foreign. It is hard to target a tumor for destruction if you don’t recognize cancer as an invader. So traditional chemotherapies have been based on the idea that cancer is rapidly growing. Powerful drugs that destroy rapidly growing cells do well against cancer, unfortunately they also damage rapidly growing normal cells, especially the hair, stomach lining, and bone marrow – hence the usual side effects from Chemo, hair falling out, nausea, and anemia.

But the latest treatments are clever – they are based on genetic differences that lead to the production of certain abnormal proteins that promote cancer growth. They take into account that certain cancers, such as melanoma, are antigenic, meaning they have surface proteins that can be used to trigger our body’s immune system in ways that can shrink the cancer.

These treatments which are less toxic and more focused are generally better tolerated and cause less side effects. Once you convince the body that cancer is foreign, you can then provoke the immune system to fight it.

Three targeted therapies for cancer made very exciting news at the annual meeting of the American Society of Clinical Oncology this past week. First, with stomach cancer, a breakthrough treatment with the use of Herceptin, a very successful drug already in regular use for breast cancer. Herceptin targets an abnormal protein found in 1/4 of women with breast cancer and decreases recurrence in 50 percent.

This protein, (HER2) was now found in high amounts in 22 percent of patients with stomach cancer. There are 21,000 new cases a year of stomach cancer in the U.S. one million new cases worldwide. In a study out of Belgium, Herceptin used in stomach cancer patients with high amounts of this abnormal protein lived three months longer than those who weren’t treated. The risk of death decreased by 26 percent.

Second, in women with extensive breast cancer, another new option was found to be useful. PARP inhibitors are chemicals which keep cancer from repairing its damaged genes. Breast cancer patients who received this lived twice as long, an average of 9.2 months, even with extensive cancer. This treatment is exciting because it stops only the cancer from repairing itself, NOT normal tissue. It may be especially useful in patients where breast cancer is linked to specific genetic abnormalities such as BRCA gene.

Third, a cancer vaccine has been developed against lymphoma, using the body’s own immune cells to fight the cancer, was shown with a small group of patients to keep them in remission for 44 months compared to 31 months for those who didn’t receive it.

These are all preliminary studies, but they together show progress in using technology, genetics, and specific therapies to help patients based on their characteristics and not just bombing cancer with a one-size-fits-all, kill-the-cancer-before-you-kill-the-body approach.

In contrast, by using tailored treatments that take into account the specifics of a patient’s cancer, you may get a better result than the shotgun poisons of chemotherapy. The research here is early but promising.

Dr. Marc Siegel is an internist and associate professor of medicine at the NYU School of Medicine. He is a FOX News medical contributor and writes a health column for the LA Times, where he examines TV and movies for medical accuracy. Dr. Siegel is the author of “False Alarm: The Truth About the Epidemic of Fear and “Bird Flu: Everything You Need to Know About the Next Pandemic.”  Read more at www.doctorsiegel.com

Healthy Smile, Healthy Wallet

Thursday, March 12th, 2009

dr-curatola1In these uncertain economic times, it is not unusual for many patients to postpone their regular preventive care. Often viewed as unimportant if there are no obvious problems and “nothing hurts,” the routine dental checkup and cleaning are put on hold in the interest of saving some money.

Unfortunately, nothing can be further from the truth. To begin with, the checkup examination can often help you avoid or detect a dental problem early before it becomes painful both physically and financially. Regular dental care helps ensure healthy teeth and gums, which in turn strengthen a healthy oral immune system.

Good oral health is essential to maintaining total body health as research continues to emerge showing a strong correlation between dental disease and many systemic problems ranging from Alzheimer’s disease to pancreatic cancer. If you are a pregnant woman, you have a seven times higher chance of having a pre-term baby. You also have up to a ten times greater chance of heart attack or stroke, and a seven times higher chance of developing type 2 diabetes. Basically, gum disease is a major source of chronic low-grade inflammation which can have ravaging effects on many body organ systems.

Several recent studies, including one completed with 145,000 patients at Columbia University’s dental school, went even one step further. They found that maintaining or restoring good oral health actually reduced total health care costs up to 21 percent for the management of patients with various systemic diseases. A study performed in Japan concluded virtually the same. The actual potential health care cost savings could easily be in the trillions of dollars if this is considered on a large population scale.

So if you’ve considered putting off your last checkup, think again. There’s a lot to be said about being “penny wise and dollar foolish.”  Now is the time to be more preventive and proactive about your health as a healthy smile is also healthy for your wallet.

Dr. Gerald P. Curatola is a renowned aesthetic dentist and pioneer in the emerging field of rejuvenation dentistry, which improves patients’ overall health and appearance by integrating total wellness with cutting edge oral care and restorative procedures. In addition to his private practice, research, and work as a Clinical Associate Professor at NYU College of Dentistry, he is an internationally sought after speaker, author and expert who has been featured widely in print and broadcast media. For more information, go to DrGerry.net

Allergy Alert: Preventing a Cold or Flu

Tuesday, October 7th, 2008

It’s that time again - to hear the familiar coughing, sneezing and other symptoms of the common cold lurking out there this fall! How are colds spread? Well they grow mainly in the nose where they increase in number.  During the first 2-4 days (when germs are most likely to spread) they are found in the in nasal secretions.   

The common cold virus is most easily spread on contaminated fingers and hands after an infected individual “touches” or rubs their nose, eyes and/or various objects and surfaces. 

A recent review of thousands of patients studied was published in the Cochrane Database of Systematic Reviews.  These studies looked at if you would receive benefit from taking daily Vitamin C (about 200mg/day).  Those who took daily Vitamin C did not see a reduction in suffering. 

However, those individuals who were “highly stressed” (for example, marathon runners) had about a 50 percent reduction in the number of days they suffered with a cold. 

Here are some avoidance strategies:

1. Don’t forget to wash your hands vigorously with soap and water for at least 20 seconds after touching various objects, surfaces or another person’s hands (it physically helps to remove cold viruses).

2. Avoid rubbing or touching your eyes and nose.

3. Avoid directly facing an individual who is coughing and sneezing.
 
3. Know that not all germicidal lotions will adequately kill cold viruses.

4. Use liquid hand sanitizers frequently, especially when hand washing is not possible.

5. Limit your exposure (even brief contact) to those “sufferers”, especially during the first several days of their cold symptoms.

6. Stay home when you are “infected” with a cold virus.

7. Indoor air purification may assist in reducing exposure and/or transmission of to airborne cold viruses, at least in some clinical studies. 

8 . Getting adequate rest and sleep,  as well as a balanced diet is a good first step in keeping your immune system from getting overly stressed and thus will be better prepared to fight off illnesses such as flu and colds.

 Dr. Clifford W. Bassett is an assistant clinical professor of medicine at the Long Island College Hospital and on the faculty of NYU School of Medicine.  He is the current vice chair for public education committee of the American Academy of Allergy, Asthma and Immunology.  No information in this blog is intended as medical advice to any reader or intended to diagnose or treat any medical condition.

Bernie Mac and Sarcoidosis

Tuesday, August 12th, 2008

Sarcoidosis is known for its deep swirls of inflammation called granulomas. This rare disease is probably due to a disruption of the immune system, either by a virus or toxin, and it certainly runs in families. Black people are affected at least three times more often than whites, (35 cases per 100,000 compared to 10 cases per hundred thousand), and this health disparity is most disturbing in terms of outcome, with 13 times more deaths in blacks.

This is because sarcoidosis, which can involve the lungs, lymph nodes, eyes, and brain, tends to affect black people at a younger age (comedian Bernie Mac got the disease in the 1980s), and is far more likely to be chronic or recurrent in blacks, as it was with the famous comedian. Despite Mac’s publicist’s assertion that his sarcoidosis was in remission and hadn’t sickened him since 2005, and despite his statement that it wasn’t a factor in his deadly pneumonia, I find this difficult to believe.

My take is that Bernie Mac most likely fell in the group of 20 to 30 percent of sarcoid patients who end up with severely scarred lungs with little reserve lung capacity left. I think Mac’s more than two decades battling the disease (the mainstay of treatment is the steroid prednisone) speaks to the probability that his lungs were no longer in shape to fight off bacteria.

Pneumonia doesn’t usually kill a 50 year old unless the patient has badly damaged lungs to begin with. In that case, an infection can quickly rifle through the scar tissue and fill what’s left of the lungs with pus and fluid. The lungs die, and the patient does too.

I suspect Mac would have wanted his death to serve as a wake-up call for early diagnosis and treatment of chronic lung diseases. Most sarcoidosis can be suspected by the findings on a simple chest x-ray, and though the majority of cases go away without treatment, it still makes sense to be vigilant.

I remember when a physician, Dr. C., came to see me for a routine physical, and the swellings in the center of his chest x-ray made me immediately suspicious of sarcoidosis. When I uttered my concern, he became so anxious that he fainted and fell off his chair. Luckily, he wasn’t hurt in the fall, and though he did turn out to have the disease, he was also in the majority group (which unfortunately Mac was not) where it remitted spontaneously.

Dr. C’s case, like Mac’s, was a reminder to me that sarcoidosis is a puzzling, unpredictable, scary disease that needs to be approached rationally rather than emotionally.

Marc Siegel MD is an internist and associate professor of medicine at the NYU School of Medicine. He is a Fox News Medical Contributor and writes a health column for LA Times, where he examines TV and movies for medical accuracy. Dr. Siegel is the author of False Alarm: the Truth About the Epidemic of Fear (Wiley 2005) and Bird Flu: Everything You Need to Know About the Next Pandemic (Wiley 2006). Read more at www.doctorsiegel.com

Dr. Manny’s Notes: Latin Powerfood #4 – Garlic

Monday, July 7th, 2008

Use garlic as often as you can in your cooking. Garlic is well known for its immune-boosting and antimicrobial properties. It also helps lower bad cholesterol. A clove of garlic a day can keep the doctor away! You will benefit from improved blood circulation as well as a stronger libido. The Spanish, Portuguese, and French are credited with introducing this powerfood to the New World, where it is now a ubiquitous ingredient.

And the best part is, you can add it to almost anything to punch up the flavor!

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