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Posts Tagged ‘Tamiflu’

Buyer Beware: Your Health May Be in Danger!

Thursday, October 15th, 2009

dr_manny_blog2With concern over the H1N1 flu reaching an all-time high – Americans are scrambling to find ways to either prevent the virus, cure it if they get it or try to get out of getting the flu shot. And as a result, many people are turning to the Internet for help.

I have said it a thousand times and I’ll say it again: It’s not safe to buy medication over the Internet from sources that are not reputable!  There are thousands of medications available on the Web, and more and more companies are popping up each day offering fast access and delivery of both over-the-counter and prescription medications. We know the dangers associated with buying drugs online, but for some reason, people continue to do it!

In fact, it poses such a problem, that in the midst of the H1N1 flu pandemic and the hysteria it’s created, the FDA felt the need to warn consumers about purchasing products over the Internet that claim to diagnose, prevent, treat or cure the H1N1 flu virus. Trust me — nothing could be more dangerous than thinking that you can fight the H1N1 virus with unregulated medications available on the Web.

The FDA issued the warning after the agency purchased and analyzed several products online that were marketed as Tamiflu, which is an antiviral drug that slows the severity of the flu. After checking out the products, many of them were found to be unsafe.

Here is an excerpt taken directly from the FDA press release:

“One of the orders, which arrived in an unmarked envelope with a postmark from India, consisted of unlabeled, white tablets taped between two pieces of paper. When analyzed by the FDA, the tablets were found to contain talc and acetaminophen, but none of the active ingredient oseltamivir. The Web site disappeared shortly after the FDA placed the order. At the same time, the FDA also purchased four other products purported to diagnose, prevent, treat or cure the H1N1 influenza virus from other Web sites.”

The products that the FDA analyzed contained varying levels of oseltamivir, and were not approved in the U.S. And furthermore if you’re ordering medications from other countries, most of them will not even arrive in time to treat someone suffering from the H1N1 flu! It’s just not worth it, people! When you order medications that are not regulated, you’re putting yourself and/or your loved ones at risk for getting counterfeit or contaminated products, and the effects can be deadly.

So instead of logging onto the Internet the next time you need a prescription drug – pick up the phone and call your doctor. After all — that’s what we’re here for.

 Click here for more information from the FDA on how to protect yourself.

H1N1 Swine Flu – What You Need to Know

Friday, September 11th, 2009

siegel1If you are a child:

  • Children have not shown any immunity to this new strain of flu.
  • Kids are super spreaders of flu, with schools being petri dishes for spread.
  • Children should wash hands frequently for at least 30 seconds with soap and water, use hand sanitizers, and sneeze or cough into their sleeve.
  • Children who have fatigue, fever, sore throat, nausea, or muscle aches, should STAY HOME and the family pediatrician should be consulted.
  • Rapid flu tests are about 60% sensitive for H1N1 swine flu, and a presumptive diagnosis can be made by a child’s doctor, based on symptoms.
  • Kids with the flu should stay home for at least two days after symptoms resolve.
  • The H1N1 swine flu vaccine will be available beginning in late October. ALL children should take it, especially those with chronic illnesses. It will likely be offered in schools. It is not clear yet whether children will require one or two shots.
  • The use of Tamiflu (anti-viral) in children is somewhat controversial; recent studies from the UK appear to show that it isn’t well tolerated or effective, though previous studies have shown that it is safe, shortens the course of illness, and can also prevent spread (80-95%) if given to close contacts. This was the experience of several summer camps in Maine this summer, where Tamiflu was also well tolerated.
  • Secondary bacterial infections are common, and should be treated promptly with antibiotics.

 

If you are an adult:

  • Especially at risk are adults with chronic illnesses such as COPD, Crohns Disease, Rheumatoid Arthritis, HIV, cancer, etc. These patients should be especially careful, take Tamiflu early for flu symptoms, be on the lookout for secondary infections including bronchitis, pneumonia, sinus and ear infections.
  • The H1N1 vaccine should be given to these groups as soon as available, as well as pregnant women (currently in clinical trials), health care workers, and close contacts of those with chronic conditions.
  • New studies just published in the New England Journal of Medicine show that the new vaccine works in 7-10 days, is well tolerated, and provides immunity with a single dose.
  • Elderly patients appear to have partial immunity to this H1N1 swine flu strain, if born before 1957, probably because of exposure to a related virus when they were younger, but should still be considered for this vaccine, especially if they have chronic medical conditions.
  • Those who had H1N1 swine flu in the Spring or Summer are likely immune. There may be a blood test available to test this.

 

Dr. Marc Siegel is an internist and associate professor of medicine at the NYU School of Medicine. He is a FOX News medical contributor and writes a health column for the LA Times, where he examines TV and movies for medical accuracy. Dr. Siegel’s new Ebook: Swine Flu; the New Pandemic, will be published in early October. Dr. Siegel is also the author of “False Alarm: The Truth About the Epidemic of Fear and “Bird Flu: Everything You Need to Know About the Next Pandemic.” Read more at www.doctorsiegel.com

Swine Flu at Camp

Monday, July 27th, 2009

siegel1I have long been concerned about potential overuse of the anti-flu drug Tamiflu, in fact there are sections on this topic in both my book on fear and my book on flu. But in my opinion, the current situation with H1N1 swine flu calls for the careful use of Tamiflu at large camp outbreaks. Use of the drug is warranted to help decrease shedding time in patients with mild cases and to prevent additional cases in their close contacts.

The CDC does not agree with me.

Here are the plusses:

1 – Since Tamiflu is highly successful at slowing spread, its use to squash outbreaks can help keep camps open which has the added benefit of keeping sick kids from bringing flu home to many different zip codes and thereby expanding the outbreak. People who are more at risk (including pregnant women, infants, and those with chronic conditions) may catch it that way. Even though this is a mild virus so far, with millions of cases around the world and only 700 plus deaths, there is always the chance that it will get worse; in fact a recent study shows that it lingers in the lungs of Ferrets (who react to flu like humans), causing lung infections.

2 – More circulating virus may increase the chance of a lethal mutation. The famous second mutation that may have occurred in 1918, when the virus became much more severe in time for the fall flu season, is extremely unlikely, but possible.

3 – Children seem more at risk for severe cases, perhaps because of a lack of immunity to an older H1N1 virus that was circulating before 1957. Older patients who have that immunity may have milder cases.

4 – Isolation of sick people and their contacts is the first priority, but use of Tamiflu (especially when there is no vaccine available), is a useful adjunct which may help to keep the camp open.
Here are the minuses:

1 – Use of Tamiflu may increase the chance of resistance occurring. There are some excellent articles on recent Tamiflu resistance, which also demonstrate that resistance sometimes occurs spontaneously, without exposure to flu:

H1N1 swine flu – the non-sustained Danish and Japanese resistance cases were in patients taking Tamiflu prophylactically. (see New Scientist article)

The interesting case in early July of a girl from San Francisco who picked up Tamiflu resistance in Hong Kong but NEVER took Tamiflu. (see NY Times article)

And the spontaneously generated resistance to seasonal H1N1 (NOT SWINE FLU) in last year’s flu season which led to massive resistance to that strain. (See NY Times article)

2 – Tamiflu shortages could emerge (although the CDC has stockpiled 50 million dose courses, and it is difficult to envision a scenario where there is a shortage of this magnitude, especially with a vaccine in the offing.

3 – Potential side effects of Tamiflu, including nausea, or an allergic reaction. But side effects are rare, Tamiflu is a very well tolerated drug overall.

4 – By having the flu now, when it is mild, a person should be immune later on, during flu season, when the flu could return in a more severe form.

I must admit, some of what drove me to put my own 12 year old son on Tamiflu prophylaxis at Camp Modin where there were more than 80 cases was because I have a 4 year old son at home with asthma and chronic ear infections. I was worried about my older son bringing the flu home. But my own scenario was far from unique, which is why I recommended that all of Camp Modin take Tamiflu.

My article on the Modin Protocol I created was published in Slate on July 10th. (see Slate article)

This was followed by a front page article by Tamar Lewin this past Thursday July 23d in the NY Times which described the problem – and solution – at the camp. (see NY Times article)

The following day, Dr. Anne Schuchat, director of the National Center on Immunization and Respiratory Diseases at the CDC, reacted to the Times article by disagreeing with camps using Tamiflu to control outbreaks. She said she “strongly recommended” giving the drug only to people already seriously ill, or to their family members who are pregnant, have asthma or have other conditions that could be life-threatening if they caught the flu.

Finally, on Saturday, July 25th, Donald McNeil wrote an excellent balanced article in the Times describing Camp Modin’s use of Tamiflu, the rationale for my advice compared to the reasons for the CDC’s disagreement. (See NY Times article)

Dr. Marc Siegel is an internist and associate professor of medicine at the NYU School of Medicine. He is a FOX News medical contributor and writes a health column for the LA Times, where he examines TV and movies for medical accuracy. Dr. Siegel is the author of “False Alarm: The Truth About the Epidemic of Fear and “Bird Flu: Everything You Need to Know About the Next Pandemic.” Read more at www.doctorsiegel.com

Obama and Swine Flu

Friday, May 15th, 2009

siegel1 I don’t want to be picky, but I have to admit that as a fear expert I was more affected by President Obama’s statement a few weeks ago in response to the emerging swine flu threat that we should all wash our hands, then I was to Vice President Biden’s blatant misstatement about not flying on planes. Let me explain: clearly, we carry many bacteria and viruses on our hands, and in fact most of our stomach viruses as well as cold viruses are passed back and forth this way. It is hard to fault anyone for recommending hand washing, but consider that Obama’s statement carried the subliminal message that we might be carrying this virus, despite the fact that the statistical chances of that then and now remain extremely low.

The president followed that up by asking Congress for $1.5 billion to prepare us for this flu, an amount that seems totally reasonable until you consider what other health care needs it might be taken away from. Stockpiles of the anti-flu drug Tamiflu will have to be discarded if they aren’t used in 5 years, and we still have no idea what the extent of spread or severity of this swine flu virus will be. Preparing a vaccine seems wise, taking needed resources away from current pandemics like TB, HIV, or even the yearly flu does not.   It is paramount that at a time when our government is considering expanding the system for health coverage, that issues of allocation and proper use of resources be at the top of the list.

The Centers for Disease Control and Prevention has been front and center during the initial stages of the swine flu outbreak, and they have been very effective at identifying and tracking the virus, somewhat less effective at explaining it in context during press conferences (this may have something to do with the nature of the beast – press conferences themselves immediately become amplified).

I have more of a bone to pick with the World Health Organization in terms of their poor conveyance of contextual information. The WHO all too often seems like “fright night” though they too have been tremendous when it comes to “boots on the ground.”

Check out my article in today’s Slate magazine about how the WHO has dealt with swine flu.

Dr. Marc Siegel is an internist and associate professor of medicine at the NYU School of Medicine. He is a FOX News medical contributor and writes a health column for the LA Times, where he examines TV and movies for medical accuracy. Dr. Siegel is the author of “False Alarm: The Truth About the Epidemic of Fear and “Bird Flu: Everything You Need to Know About the Next Pandemic.”  Read more at www.doctorsiegel.com

The Legacy of H1N1

Thursday, May 7th, 2009

siegel1As we watch swine flu through the rear view mirror, and our concerns begin to fade, it is easier to see it in a more proper context. I tried to do just that in my oped in USA Today.

Even as we turn our attention to the southern hemisphere, and watch via the World Health Organization FluNet tracking system for the extent of the virus over the winter, I can’t help but comment on the WHO handling of the Pandemic Alert System as it applies to the swine flu outbreak.

The problem is that the current alert system was put in place in 2005 in reaction to the Avian Flu scare. Of course a tracking system in response to a scare has a built in tendency for overreaction. I don’t have a problem with the notion that level 5 involves sustained transmission of a new flu strain from person to person in 2 countries in the same region. Nor do I have a problem with the idea that a full pandemic (a scare term which is too vague to be descriptive) involves a sustained outbreak in different regions of the world. What I do have a problem with is the lack of statistics —number of cases and number of deaths don’t factor in. So it is possible to have a pandemic with only a few thousand cases. Where would the Bubonic Plague or the Spanish Flu, diseases which killed many millions of people, fit on a pandemic alert scale where a relatively small outbreak of Swine Flu is already listed near the worst possible ranking?

Not only that, but these pandemic alerts are used by the U.S. and other countries as a justification to divert needed health resources from other essential medical problems to the fear of pandemics. Sometimes that is justified, but often it isn’t. Keep in mind that Tamiflu and vaccines (which are stockpiled and then mobilized in anticipation of a pandemic), are perishable. We have already discarded hundreds of thousands of doses of unused smallpox and anthrax vaccines. How much excess expensive Tamiflu will we also discard when it expires?

Dr. Marc Siegel is an internist and associate professor of medicine at the NYU School of Medicine. He is a FOX News medical contributor and writes a health column for the LA Times, where he examines TV and movies for medical accuracy. Dr. Siegel is the author of “False Alarm: The Truth About the Epidemic of Fear and “Bird Flu: Everything You Need to Know About the Next Pandemic.”  Read more at www.doctorsiegel.com

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